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This dual agonism represents a novel pharmacological approach, targeting two complementary incretin pathways simultaneously rather than one

FIGURE 2 The random-effects relative treatment estimates versus metformin are shown in Figure 2B, followed by exploratory SUCRA and rank-probability summaries in Figures 2C,D and posterior density/ROPE summaries in Figure 2E

In this role, pharmacists serve as advocates, educators, and partners in caretransforming weight management from a daunting challenge into a supported, achievable journey

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The medication addresses the physiological mechanisms that drive hunger and weight rebound, making it especially valuable for individuals who lose weight initially but struggle with long-term maintenance