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This leads respectively to the formation of a glutathione adduct (S-SG) and of a persulfide group (S-SH), two reversible modifications referred to as glutathionylation and persulfidation

That said, combining injectable and topical approaches creates a two-pronged strategy that addresses skin from both the inside out and the outside in

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The physiological requirements for cysteine can be met by dietary cysteine or by an excess of dietary methionine