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Norepinephrine is the key neurotransmitter responsible for regulating blood pressure and heart rate at rest

These variants are also important in susceptibility to opiate addiction

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It is interesting to note that the positive effect of tirzepatide on body weight is associated with a significant improvement in quality of life and physical performance [50] and is independent of sex [51], baseline body mass index (BMI) [52] and potential side effects, predominantly gastrointestinal [53]