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Many patients report feeling full after much smaller portions, while others notice mild constipation or occasional dizziness if hydration or calorie intake decreases

How Isotretinoin Affects Moisture Isotretinoin reduces sebaceous gland activity and sebum production

(Reporting by Maggie Fick and Bhanvi Satija in London

[68] [69] However, a 2025 meta-analytic systematic review of 113 randomized controlled trials found that stimulant medications were the only intervention with robust short-term efficacy, and were associated with lower all-cause treatment discontinuation rates than non-stimulant medications (e.g., atomoxetine)

doi:10.1002/0471264180.or017.03