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CagriSema (semaglutide + cagrilintide), filed by Novo Nordisk in December 2025, achieved 22.7% weight loss in trials and could receive FDA approval in 2026
Inflammatory cytokines can amplify OS, creating a vicious cycle that leads to further nerve injury
Fifth, previous CVOTs have suggested that the beneficial effects of GLP-1 RAs are primarily associated with long-acting agents such as liraglutide, semaglutide, and dulaglutide, rather than short-acting agents like exenatide and lixisenatide [17, 54, 56, 57, 68]
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