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In other studies, it has been shown that staurosporine-induced activation of apoptosis is mediated by ROS (Shimizu et al., 2004
[15] A recent study on melasma patients noted significantly higher levels of glutathione-peroxidase enzyme in patients compared to controls, confirming the role of oxidative stress in melasma
(2) The Human Evidence Gap No completed, peer-reviewed Phase II or Phase III randomized controlled trials in humans have been published as of July 2025
Statistical analysis between groups was performed using MannWhitney and KruskalWallis tests
Food intake and body weight were measured twice weekly
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