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Notably, the azo-containing chemotherapeutic drug procarbazine for the treatment of Hodgkins lymphoma and brain cancers was found to interact through a similar mechanism of action involving the transformation of GSH to GSSG and regeneration of the catalyst through a reaction with O 2 38,39 , providing feasibility of the proposed catalysis

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A total of 19 differentially regulated protein spots were identified, of which 18 spots were up-regulated and 1 spot was down-regulated in non-splenectomized -thalassemia/HbE as compared to normal controls (Fig

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10 (Suppl 2):S8S24

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