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These studies provided scientific support for the use of MO by indigenous Philippines and Indians who collected MO to dress wounds (Nama, 2015

Figure 4 Alterations in the intracellular redox status are often associated with GSH depletion (Polonikov, 2020) and endogenous GSH deficiency, due either to decreased biosynthesis and/or increased consumption, is a marked contributor to the pathogenesis of numerous diseases via mechanisms including oxidative stress and inflammation

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Notably, rodents have only the first four GPx isoenzymes (GPx1-GPx4) as the selenoenzymes and the remaining four (GPx4-GPx8) as the cysteine-containing enzymes [1, 8, 9]