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doi: 10.2337/db08-0958 131 NauckMAHeimesaatMMBehleKHolstJJNauckMSRitzelRet al

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Data extraction, risk of bias assessment, and meta-analysis were performed using standardized methods with a random-effects model

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The headline On Thursday 21 May 2026, Eli Lilly announced that participants in TRIUMPH-1, the first Phase 3 trial of retatrutide in obesity, lost an average of 28.3% of their body weight at 80 weeks on the 12 mg dose, with 45.3% losing at least 30% of their starting weight [1]

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