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General sexual dysfunction treatment: According to King et al., melanocortin agonists like PT-141 have possible applications to the unmet medical needs of decreased sexual motivation and loss of libido [14]
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It differs from the native 70 residue growth factor by an arginine-for-glutamate substitution at position 3 and a hydrophobic 13 residue N-terminal extension, MFPAMPLLSLFVN, which is itself a residual fragment of the methionyl porcine growth hormone fusion partner used to express the protein in Escherichia coli
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