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A 5% decrease in lean mass sounds concerning until you consider it accompanied 20% total weight loss and 30% fat mass reduction

For many patients, they succeeded where years of diet changes, exercise programs and other medications had failed

The PI3K/Akt signaling pathway, which maintains protein balance, is inhibited under catabolic conditions such as sepsis, inflammation and immobilization, promoting UPS activation and protein degradation (68)

There was no difference in the risk of CV death when GLP-1RA were compared with SGLT-2 inhibitors

When practitioners rely on GLP-1s as a standalone tool, we risk overlooking the deeper patterns driving weight changes in perimenopause