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This typically happens somewhere between months 3 and 6 and can feel like the medication has stopped working entirely
A key conceptual priority for the field will be to distinguish direct signal transmission from the propagation of ferroptosis susceptibility states, as these processes may reflect fundamentally different modes of tissue-level coordination
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Autophagy exhibits selectivity in degrading certain cargoes such as mitochondria (mitophagy) endoplasmic reticulum (reticulophagy), intracellular microbes (xenophagy), lipid droplets (lipophagy), peroxisomes (pexophagy) and glycogen (glyophagy) or non-selective to degrade random parts of the cytoplasm (144)
