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(May 2001)

First, by binding free Cu with picomolar affinity, it prevents copper from participating in Fenton chemistry (Cu + HO Cu + OH + OH)

However, iron triggers the formation of free radicals via Fenton and Haber Weiss reactions during various metabolic activities [61,84] and presence of hesperidin before iron treatment might have blocked the generation of ironinduced free radicals resulting in the decline in iron-induced oxidative stress in the mice kidney

57 LiZ.RanaT

On a day-to-day basis, our bodies are equipped to manage oxidative stress, however, with regular and excessive alcohol consumption, our body cannot keep repairing the damage leading to a state of oxidative stress