Sections (5 mm) were stained with Safranin-O/Fast Green and hematoxylin and eosin
PDH catalyzes the formation of acetyl coenzyme A, a crucial step in energy production, and, through acetyl-CoA, serves as a precursor for acetylcholine (ACh), which is vital for nerve signal transmission and muscle function since ACh acts on the communication between neurons and in the neuromuscular junction, as well as for myelin production in nerve cells (36, 39, 40)
That is the most honest framing Tatem can offer for a combination that has genuine potential but no superhero track record
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For instance, NSAIDs can inhibit COX-1 and COX-2, which are involved in the production of pro-inflammatory prostaglandins (Turner et al., 2014)