Protection & Repair: It serves as a skin bodyguard against environmental damage, UV radiation, and pollution, aiding in repair
It has been used: As part of the treatment for cyanide poisoning To dye tissues during surgery to determine tumors To relieve pain caused by oral mucositis To identify orthopedic injury to joint capsules To treat malaria before modern treatments were developed To treat encephalopathy, or confusion caused by chemotherapy Exploring other uses for methylene blue Earlier in my career, while working in emergency medicine, I read two papers that discussed using methylene blue as part of photodynamic therapy for lichen planus, a type of precancerous lesion in the mouth
Signs you're using too high a concentration include persistent redness, increased sensitivity to other products, dryness that doesn't respond to moisturizer, and skin that looks worse rather than better over time
Baudouin-Cornu P et al
The roles of complexes III and IV in apoptosis are less clear, but the electron carrier between the two complexes, cyt c , has been known as a key player by activating apoptosis protease activating factor-1 (Apaf-1) when released to the cytosol