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SG disassembly defect associated with pathogenic VCP mutations can be rescued by mimicking ULK-mediated phosphorylation or ASPL knockdown Mutations affecting the R155 position of VCP account for almost 50% of cases of MSP ( 41 , 71 )
Regulatory status (US) FDA-approved prescription drugs These compounds work through different mechanisms and are not interchangeable
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10.1104/pp.116.1.37 23 DatJ.VandenabeeleS.VranovE.Van MontaguM.InzD.Van reusegemF
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