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The US Food and Drug Administration (FDA) has approved Wegovy to: Reduce body weight and support long-term weight loss in people with obesity or with overweight and a weight-related health condition, such as type 2 diabetes or sleep apnea Reduce the risk of experiencing a major cardiovascular event , such as heart attack, stroke, or death, in people with heart disease and obesity or overweight Typically, healthcare providers prescribe a starting dose of 0.25 mg weekly