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Lactate modulates the level of N 6 -methyladenosine (m 6 A) modification by enhancing the binding of lysine 18 on histone H3 acetylated by lysine acetyltransferase p300 (H3K18ac)[208] to the METTL3 promoter site

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anaphylaxis is rare (less than 1 in 1,000) but constitutes a medical emergency

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