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The MT-II scaffold has since generated a large derivative family through substitutions at positions 6, 7 and 9, including N-methylated variants used to obtain MC1R selectivity

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This technique has been used successfully to treat urinary retention and urinary and fecal incontinence, and has more recently been employed to treat chronic constipation

Ten peptyd zyska zainteresowanie, poniewa wedug dostpnych bada moe wpywa na procesy zwizane z regeneracj tkanek, angiogenez, czyli tworzeniem nowych naczy krwiononych, ochron bony luzowej przewodu pokarmowego, modulacj stanu zapalnego oraz napraw uszkodzonych struktur miniowo-cignistych