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FOXO4-DRI is a D-retro-inverso peptide designed to interfere with the interaction between the FOXO4 transcription factor and p53, a key mechanism that senescent cells exploit to resist apoptosis

This approach is based on individual tolerance preference, not thyroid safety data, as there is no evidence that lower doses carry different thyroid risk profiles than standard doses

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Following months are $400 each, which includes follow-up appointments at 4, 8, and 12 weeks

David Sinclair, Life Biosciences co-founder (Jemal Countess/Getty Images for TIME) April 8, 2026 08:00 AM EDTUpdated 08:41 AM Financing Startups Cell/Gene Tx David Sinclair startup raises $80M for clinical test of anti-aging gene therapy Ryan Cross Senior Science Correspondent A startup developing a one-time treatment that is intended to rewind the clock on dying cells announced a major influx of funding