When weight falls, muscle can follow, and that loss changes how you move, how clothes fit, and how you feel day to day
probiotics as well as prebiotics have been demonstrated to exert multiple beneficial effects in IBD (186) and T2D (187), including increased GLP-1 release (188)
Risk factors that may prompt additional consideration include: Active gastrointestinal symptoms (nausea, vomiting, abdominal pain) Recent dose increases or being in the dose-escalation phase Higher doses of semaglutide Known gastroparesis or other conditions affecting gastric emptying Obesity with GERD or hiatal hernia Based on the 2024 multi-society guidance, most patients can continue GLP-1 receptor agonists before elective procedures with appropriate risk assessment and mitigation strategies, rather than automatic postponement
GLP-1s finally give biology-level help
How to manage fatigue while on semaglutide The good news is that fatigue on semaglutide is usually manageable and often improves with time