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The LKKTET(Q) motif binds G-actin, buffering monomers and regulating polymerization so cells can rapidly reorganize their cytoskeleton and move into injured tissue
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Au HCT, Lam PH, Lim PK, McIntyre RS (2025) Role of Glucagon-Like Peptide-1 on Amyloid, Tau, and -Synuclein: Target Engagement and Rationale for the Development in Neurodegenerative Disorders
However, these results have been controversial and the clinical relevance has been questioned since endothelial cells in human glioblastoma have not been observed to harbor genetic alterations in other studies [78, 79]
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