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If you switch from a compounded semaglutide with B12 to a formulation without it (or to brand-name Wegovy, which does not contain B12), you need to add B12 supplementation separately

Modulation of NAD+ and SAM Levels : 5-Amino-1MQ has been observed to elevate intracellular NAD+ concentrations by reducing methylation loss, a process that indirectly enhances mitochondrial redox capacity

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(2000) Metabolic Studies of a Synthetic Lipolytic Domain (AOD9604) of Human Growth Hormone Horm Res 53(6):274278

They aren't substitutes for one another they're tools matched to different mechanistic questions in metabolic research