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They also intensify dietary restriction and restraint and exacerbate symptoms associated with starvation (e.g., irritability, preoccupation with food, fatigue, and social indifference), reinforcing the primary maintaining mechanisms of this eating disorder

GLP-1 RAs, including oral semaglutide, offer promising solutions due to their effectiveness in glycemic control, weight management, and cardiorenal protection compared to DPP-4 inhibitors and many SGLT2 inhibitors

Appetite is complex, influenced by hormones, habits, emotions, sleep, hydration, and nutritional quality

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