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Lean mass loss accelerates, resting metabolic rate drops, and the rebound when appetite normalizes is more severe
However, this is not very different from other weight loss injections
Some newer agents permit less frequent dosingfor example, retatrutide and certain long-acting formulations may allow biweekly or monthly administration
Tardito D, Mori S, Racagni G, Smeraldi E, Zanardi R, Perez J
Because body composition, eating patterns, and health behaviors differ around the world, the authors emphasized the need to understand how these drugs work in more diverse populations
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