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312 Lipotoxicity impairs insulin signaling, induces oxidative damage, promotes inflammation and fibrosis, 313 which is thought to be related to the progression of MAFLD patients from simple steatosis to NASH, hepatic fibrosis, and hepatocellular carcinoma

Ming Zhang, Wenjuan Han, Sanjue Hu, Hui Xu

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Chronic neuroinflammation, oxidative stress, and impaired glucose metabolism in the brain are also recognized as contributing factors to disease pathogenesis

If youre someone who eats a high-fat diet and wants to block some of that fat absorption, chitosan might be worth a tryprovided youre not allergic to shellfish