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After demonstrating the anti-parasitic effect in vitro , we performed untargeted metabolomics on parasites treated with 30 M of SFN for 3 h, and the most significantly elevated metabolites in treated cells compared to controls were SFN-thiol adducts, including SFN-GSH and SFN-Cysteine
The drugs efficacy in obese adolescents was also notable, with significant reductions in BMI and higher proportions achieving over 5% and 10% weight loss compared to placebo [38]
Biochemical mechanisms for oxygen free radical formation during exercise
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