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Tirzepatide, the first dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) RA approved for both conditions, has paved the way for next-generation incretin-based therapies

[53] In 2023, a cryo-electron microscopy study reported a 1.55 structure of the Escherichia coli 70S ribosome in the translating state, providing near-atomic detail of rRNA modifications, tRNA-mRNA interactions, and ion coordination