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In May 2025, Aon released the first phase of a US study of GLP-1 medications for diabetes and weight management
In trastuzumab-resistant Her2-positive breast cancer cells, IGFBP-3 expression was reduced, leading to the inhibition of Wnt signaling pathway release and increased Cullin7 expression mediated by TCF7L2
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However, we found that the exendin-4 antibody light chain fusion (Ab#2_EX4) had a GLP-1R activity half-life of 11 h, with no improvement seen in stability over the Ab#2_GLP1 fusion molecule (Fig
Mild discomfort that typically subsides quickly
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