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It was found through collaborative stable isotope labeling in cell culture (SILAC) and mass spectrometric analysis of glioblastoma cells modified to overexpress SLC7A11, that mTORC2 (mammalian target of rapamycin complex 2) binds to the N-terminal cytoplasmic tail of SLC7A11 and inhibits its transport activity via phosphorylation at serine 26 (43)
For acute stroke or TBI, high doses are standard
Washington: HHS and USDA, 2020
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