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An increase in both Growth Hormone (GH) and its downstream partner, Insulin-like Growth Factor 1 (IGF-1), can have a significant effect on the kidneys

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PubMed laboratory research record [PMID: 42288971] PubMed record related to this compound for laboratory literature review

doi: 10.1007/s00405-016-4066-6 25 WoessmannWNeugebauerMGossenRBlutters-SawatzkiRReiterA

And so it is important that these medications are prescribed in the setting of a comprehensive weight management program so that patients can do the other parts of healthy weight management to maintain their health and their muscle mass