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Gene specific primers for mitochondrial markers such as cytochrome c oxidase subunit 5a (COX5a), dynamin-related protein 1 (DRP1), mitochondrial calcium uniporter (MCU), peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC1), and pro-apoptotic markers (Bax and Bad) were designed as shown in Supplementary Table 1

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