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The most serious occurred in the placebo arm: cholecystitis requiring cholecystectomy

Segn el artculo publicado por la revista The Lancet , si se prescriben los agonistas del receptor GLP-1 sin un apoyo nutricional adecuado, existe una probabilidad de recada con riesgo de desnutricin, lo que empeora los efectos de la obesidad en el microbioma (12)

By activating GLP-1 receptors in the hypothalamus and other appetite centers, semaglutide reduces calorie intake by suppressing hunger cues

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