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Inhibition of tyrosinase remarkably affects the levels of melanin, skin colouring pigment

PMID: 28955242

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Constipation may also predispose bacteria to reach excessive populations, particularly Lactobacillus species that can execute tyrosine decarboxylation, L-DOPA by converting it into dopamine in the gut hence limiting its release into the bloodstream and causing motor fluctuations (Menozzi and Schapira, 2024)

Their cortisol may not be low enough for Addisons or high enough for Cushings, but they still experience fatigue, brain fog, poor sleep, and other symptoms