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Expert Opinion on Drug Safety , 18
Hypokalemia (low potassium) is a known risk with insulin therapy, especially in medically complex situations
GLP-1, acting on its receptor, has physiological actions on multiple target organs: it increases glucose-stimulated insulin secretion in pancreatic beta cells, reduces glucagon secretion by cells, improves insulin sensitivity and reduces food intake.26 In cellular and murine models GLP-1 promotes cell neogenesis and inhibits their apoptosis.27 Insulin secretion induced by GLP-1 is dependent of the glycemia and therefore does not induce hypoglycemia (Fig
Kelley N, Jeltema D, Duan Y, He Y (2019) The NLRP3 inflammasome: an overview of mechanisms of activation and regulation
These differences in adherence rates across various medications and use cases are illustrated in Figure 3
