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Protection of the C-terminus is achieved via substitution of a glycine for the native proline at residue 171 (P171G) relative to mature (i.e., signal peptide removed) human FGF21, preventing degradation by FAP

Wegovy is also an injection, but is used for the treatment of obesity

These limitations affect the overall assessment of copper peptide safety and regulatory approval decisions

Limitations and Mixed Results Many studies have small sample sizes or short durations, making it hard to draw firm conclusions

Most skin types, including oily, dry, sensitive, acne-prone, and combination, tolerate it well when its formulation is correct