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MC1R affinity is therefore roughly an order of magnitude higher than at the other three subtypes, a preference rather than selectivity in the strict pharmacological sense

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The weight loss from bupropion alone is modest, typically 2-5% of body weight over several months, and it is often categorized as "weight-neutral" compared to other antidepressants rather than as a weight loss medication per se

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This may include strategies for managing stress, overcoming emotional eating triggers, and building sustainable lifestyle changes

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Shaking can cause the delicate peptide chains to break apart, a process called denaturation

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Most clinicians may not have the knowledge to do this

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