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What we need to be thinking about is not only how we can create more GLP-1, but how we can restore our sensitivity to it so that we can feel full after eating. Natural Ways to Boost GLP-1 While research shows that GLP-1 medications are more effective than lifestyle tweaks to improve your GLP-1 (8), the following may modestly support weight management by promoting incretin sensitivity and bumping up your GLP-1 levels, according to physician Simran Malhotra, M.D
In this situation, combination therapy shows unique advantages, CPT (an NRF2 inhibitor) (139), anti-angiogenic drugs (140), immune drugs (PD-1 inhibitors), etc
Lucia M Ruiz-Perera et al
Alpha-Lipoic Acid (ALA): This is another antioxidant that works inside the mitochondria (the powerhouses of your cells)
On safety, the published Phase 2 data reported that gastrointestinal effects nausea, vomiting, and constipation among them were the most common adverse events, were generally mild to moderate, and usually occurred during the escalation phase of the protocol
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