the median follow-up is estimated to be nearly 2 years
Individuals with a personal or family history of thyroid tumours should be aware that, in common with other GLP-1 receptor agonists, retatrutide's GLP-1 activity may carry a theoretical thyroid risk
2.3.3 Molecular pathogenesis and disease mechanisms The development of ALS is driven by several overlapping biological mechanisms that together cause motor neuron degeneration
Considering only events within various age groups, the ICERs indicated that SGLT2is were not cost-effective for people aged 1039 years or 4059 years for any intervention (although the ICER for SGLT2is in the secondary prevention population was 29,420), while SGLT2is were cost-effective among people aged 6079 years (ICERs of 28,002 and 328 in the primary prevention and secondary prevention populations, respectively) and 80 years, but GLP-1 RAs were not
Obes (Silver Spring) 20:330342 Colhoun HM, Lingvay I, Brown PM et al (2024) Long-term kidney outcomes of semaglutide in obesity and cardiovascular disease in the SELECT trial