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Cysteinylglycine or -glutamylcysteine have been proposed as possible alternatives.In a trial of adolescents with poorly controlled type 1 diabetes, a dose of 30-45mg/kg/day NAC failed to correct several markers of glutathione status, suggesting either a higher dose or alternative therapies may be indicated in this population.A recent study of patients with poorly controlled type 2 diabetes found that dietary supplementation of the amino acids cysteine and glycine, markers of glutathione synthesis and plasma oxidative stress were both improved
Ischemia reperfusion injury, ischemic conditioning and diabetes mellitus
doi: 10.3390/proteomes11040037 454 StepieAETrojniakJTabarkiewiczJ
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