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These agents are recommended as second-line add-on therapy in patients without clinical ASCVD

5.7 Hypersensitivity Reactions Serious hypersensitivity reactions (e.g., anaphylaxis, angioedema) have been reported in patients treated with semaglutide tablets

Additionally, liraglutide also appears to enhance the suppressive effects of Tregs, as evidenced by reduced CD8 + T cell proliferation in co-culture assays involving Tregs in mice treated with GLP-1 analogues [149]

Understanding proper peptide reconstitution and correct storage practices is essential for minimizing variability-related side effects