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Investigators administered BPC-157 by three routes intraperitoneal injection, oral administration in drinking water, and topical application as a thin cream layer with assessment over a 90-day post-injury period
Treatment significantly reduced levels of pro-inflammatory cytokines including interleukin-1 (IL-1) and tumor necrosis factor- (TNF-) while increasing anti-inflammatory interleukin-10 (IL-10) expression
These results are displayed in the forest plot in Figure 1
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Romagnani P, Remuzzi G, Glassock R, Levin A, Jager KJ, Tonelli M, Massy Z, Wanner C, Anders HJ
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