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Mechanism of Action Comparison# Retatrutide# Retatrutide (LY3437943) is a 39-amino acid synthetic peptide that simultaneously activates three metabolically important receptors: GLP-1 receptor : Enhances glucose-dependent insulin secretion, suppresses glucagon, slows gastric emptying, and reduces appetite through hypothalamic and brainstem signaling GIP receptor : Potentiates insulin secretion, may improve beta-cell survival, and contributes to adipose tissue metabolism and central appetite regulation Glucagon receptor : Increases hepatic energy expenditure, promotes fatty acid oxidation in the liver, stimulates thermogenesis in brown adipose tissue, and enhances lipolysis The glucagon receptor component is the defining innovation

Hutch CR, Sandoval D

Economic Loss: Calculated based on lost earning potential, ongoing medical costs, and other financial burdens

To maintain your results, it is important that you hydrate, take in the right amount of protein, and exercise

Accessed August 1, 2024