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Within the main cohort of approximately 2,000 participants, two baskets were enrolled based on obesity-related comorbidities: 574 participants with knee osteoarthritis and 243 with obstructive sleep apnea (OSA)
The STEP UP trial showed that Wegovy 7.2 mg produced an average 20.7% weight loss, comparable to the maximum dose of Mounjaro
Common side effects include nausea, vomiting, diarrhea, and constipation, but most of these symptoms improve over time
10.1152/physrev.00024.2010
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Body weight dropped by an average of 10 pounds
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