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56 This may be the secret of the extraordinary efficacy of tirzepatide, but it is still possible that the best ratio of GLP-1 and GIP activity in a dual agonist has not been discovered

It's important to note that Wegovy users do not need to select needle size, as the medication comes in a single-dose auto-injector with an integrated needle

Cognitive disorders Pre-clinical and mechanistic studies Our search retrieved a high number ( N = 189) of pre-clinical or mechanistic studies assessing the possible effects of GLP-1RAs on cognitive disorders, which cannot be described in the main text of this article due to space constraints (Supplementary Section 4)

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Patients should consult a qualified healthcare professional to determine whether any weight loss treatment is appropriate for their individual needs