Cancer Res 66(6):29462952 Hadley ME, Dorr RT (2006) Melanocortin peptide therapeutics: historical milestones, clinical studies and commercialization
Josephs TM, Belousoff MJ, Liang YL, Piper SJ, Cao J, Garama DJ, et al
The key difference appears to be dosage
We do have to be careful about excess body weight loss, which we know sarcopenia, bone health, and so forth but we really haven't seen any other signals to date, and we're going to continue and look for those
It is widely accepted that diabetes is not mutagenic but may be mitogenic, likely due to factors such as hyperglycemia, hyperinsulinemia, or the confounding effects of adiposity