If your pharmacy offers the same dose in a smaller volume at higher concentration, the smaller volume option typically provides better absorption because the medication is less diluted by saliva
doi: 10.3389/fnut.2026.1804917 Received 05 February 2026 Revised 04 March 2026 Accepted 16 March 2026 Published 31 March 2026 Volume 13 - 2026 Edited by Berenice M Romn Calleja, National Institute of Medical Sciences and Nutrition Salvador Zubirn, Mexico Reviewed by Anindita Banerjee, Indian Council of Medical Research (ICMR), India Venkateswararao Eeda, University of Oklahoma Health Sciences Center, United States Updates Copyright 2026 Chen, Zou, Li, Liu, Liu, Yao, Peng, Liang, Chen, Huang and Huang
For most protocols, this variation falls within acceptable tolerance
However, as an observational target trial emulation, the study cannot establish causality, and residual or unmeasured confounding remains possible
But, your doctor might change this based on how you react and your health