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Rather than targeting vascular tissues, PT-141 acts centrally in the brain through activation of melanocortin receptors located in the medial preoptic area (mPOA) of the hypothalamus, a critical region for regulating sexual behavior
It involved 48 adults who all met the criteria for alcohol use disorder (AUD)
doi:10.14740/jocmr6532 Jordan Llerena-Velastegui, Melisa Santamaria-Lasso, Melany Mejia-Mora, Andrea Granda-Munoz, Martin Trujillo-Delgado, Claudia Hurtado-Alzate, Ana Clara Fonseca Souza de Jesus, et al
But compounded versions have extra question marks: The dosing might not be as precisecompounding pharmacies dont have the same manufacturing controls as big pharma companies, so there could be variability in how much actual medication youre getting
