The peptide preferentially activates MC1R, a Gs-coupled GPCR expressed primarily on melanocytes and immune cells
Mehta M, Rometo D, Gusenoff J, Rubin JP
Distinct promoters determine alternative transcription of gpx-4 into phospholipid-hydroperoxide glutathione peroxidase variants
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[21] [3] Hepatic impairment is also relevant: vildagliptin, for example, should be avoided in patients with hepatic impairment, and liver function tests (LFTs) should be monitored during treatment as specified in its SmPC