Side effects are not common, and cyanocobalamin is considered to be a safe alternative for vitamin intake for those having trouble doing so naturally
[18] Cardiovascular monitoring should include periodic assessment of heart rate and blood pressure, particularly during the first few months of combination therapy
Clinical trial data shows that nausea, diarrhoea, and vomiting typically peak around week 20 and decrease thereafter
Further, it activates muscle stem cells, promoting tissue regeneration, and reverses insulin resistance in relevant animal models, all with good systemic tolerability 1,2
Dias S, Welton NJ, Caldwell DM, Ades AE (2010) Checking consistency in mixed treatment comparison meta-analysis